Hi @Carl Hansen and @Mimi La Bella , I understand you're seeking guidance on what to do about Defender warning on OpenSSL and Python, although there is no newer version available or your application requires a specific version of those components.
Defender lists out any vulnerability by giving "Attention required" label. It allows security administrators to use the information about the vulnerable component to evaluate the effect of any proposed remediation on the whole organization.
Then your security admin (or you, if that's your responsibility) needs to decide on what to do, there are 2 buttons available on Defender: Request remediation or Exception options.
More info: Vulnerable components
Please accept an answer if correct. Original posters help the community find answers faster by identifying the correct answer. Here is how.