@Sourav Thank you for reaching out to Microsoft Q&A.
I understand that you are having questions regarding Azure Firewall Policy. Thank you for sharing your network diagram with us. Answering your questions below:
1.If the East US region goes down, will the policy still be accessible by fw2(from West US) ?
Yes, it will be accessible. Policy is region failure resilient. If East US is down, West US will not be affected.
2.If yes then will there be any interruption on West US region's traffic because of the primary region failure ?
No, there will not be any interruption.
Hope this answers your questions. Please let us know if you have any further questions/concerns and we will be glad to assist further. Thank you!
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